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Louisiana Tech researches discover self-assembled metal-organic biohybrids can be used to deliver drugs to human body

Louisiana Tech University Biomedical Engineering and Molecular Science and Nanotechnology professors, students and alumni have published a paper on the discovery of metals-based organic biohybrids and their use in drug delivery.
The research team discovered that self-assembled metal-organic biohybrids (MOBs) can be used to deliver drugs to the human body, according to a university article.

The findings are detailed in an article, “Self-Assembled Metal–Organic Biohybrids (MOBs) Using Copper and Silver for Cell Studies,” published in Nanomaterials.

The research team includes BMES members Dr. Teresa Murray, Anik Karan and Dr. Chelsea Pernici. Also on the team: Dr. Mark DeCoster, Neha Karekar, Elnaz Khezerlou and Neela Prajapati.

The MOBs outlined in the paper consist of copper, silver and an amino acid, and the elements combine at body temperature, according to the article. The team discovered that once created, the MOBs are stable and can remain combined for years in storage. However, once they are reintroduced to cells, the MOBs are biodegradable.

In the article, DeCoster said the research is getting attention for several reasons:
  • First, the team discovered a new acronym or name for a family of materials and the process, which the call “MOBs.”
  • Second, the nanomaterials are completely biodegradable, which is not always the case.  The biodegradable nature of the MOBs means that the materials can be recycled and can be part of the delivery process, rather than just hanging around and potentially causing problems.
  • Finally, there is great interest in the metals portion, because metals have so many potential uses, even outside of biology, including energy processes, catalysis and construction materials.
Read the Louisiana Tech article HERE.

Read the Nanomaterials article HERE.