Hopkins researchers develop new way to map cancer images
Johns Hopkins Medicine researchers have developed a new approach for accurately computing and visualizing the structural and functional blood vessel changes needed for tumor growth, the university announced.Researchers compare the method to a “Google Maps” approach, according to the article.
By pairing high-quality 3D imaging data of tumor specimens from animal models with sophisticated mathematical formulas, the researchers say they now have a model that accurately represents blood traffic inside tumors, including the complex blood flow, oxygenation and structural changes that occur, it states.
This work was published in Nature Scientific Reports.
The authors include: Spyros K. Stamatelos, Akanksha Bhargava, Eugene Kim, Aleksander S. Popel and Arvind P. Pathak. Popel is a BMES member.
Pathak, Ph.D., the study's leader, says the project was developed out of the need to address the complexities of cancer biology in growing and developing tumors. He saw the need for better predictive models, as many existing models employed rudimentary approximations of the complex geometry of a tumor's blood vessels.
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