U of Penn Michael Mitchell Receives NIH Director's New Innovator Award

University of Pennsylvania's Michael Mitchell received a $2.4 million NIH Director's New Innovator Award, which is part of the NIH Common Fund's High-Risk, High-Reward Research program.
The High-Risk, High-Reward Research program supports innovative research proposals that might not prove successful in the conventional peer-review process despite their potential to advance medicine.

Mitchell is the Skirkanich Assistant Professor of Innovation in Penn Engineering's Department of Bioengineering. His reseaarch draws on a variety of fields—biomaterials engineering, data science, gene therapy and machine learning—to tailor the next generation of drug delivery vehicles with this level of precision.

According to a Penn Engineering article: “We're proposing a ‘4D' platform: data-driven drug delivery,” Mitchell said in the article. “This combines what we commonly use in drug delivery - engineering or designing new biomaterials and nanotechnologies that encapsulate drugs and getting them where they need to go - with machine learning and data science so a computer can help us identify which molecular properties of a drug delivery technology allow us to target diseased cells in the body. The hope is that one day, instead of testing these delivery systems one at a time, we can test many of them at once to define the physical and chemical parameters that make them more or less effective.”

Mitchell is a BMES member.