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U of Arkansas researchers develop method for identifying radiation-resistant tumors

New research at the University of Arkansas has found a way to identify radiation-resistant cancer cells, a breakthrough in the treatment of lung cancer that uses imaging to evaluate the response to treatment and match treatment to specific tumor cells, according to a university article.
Currently, there has been no way to determine immediately after beginning therapy if a tumor is resistant to radiation therapy or not, according to the article. The findings were published this month in Scientific Reports, a Nature journal.
 
“Our results demonstrate that the use of autofluorescence imaging of cell metabolism can identify treatment-resistant cancer cells,” said Narasimhan Rajaram in the article. Rajaram is an assistant professor of biomedical engineering at the University of Arkansas and lead researcher on the project. He is also a BMES member. “More importantly, we think that this technique provides a sound method to evaluate tumor response to treatment and match tumors to the right therapy.”
 
Using an innovative imaging system, a team of researchers from the University of Arkansas and the University of Arkansas for Medical Sciences has identified differences between the metabolic response of radiation-resistant and radiation-sensitive lung cancer cells following therapy.

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