Ga Tech, Emory researcher Michael Davis researches stem cell therapies and 3D printing related to pediatric cardiology
Michael Davis, director of the Children's Heart Research and Outcomes Center (HeRO) under the Georgia Tech and Emory University's Department of Biomedical Engineering is using stem cell research, predictive medicine models and 3D printing to treat pediatric cardiology issues.According to a Georgia Tech article, a few years ago, Davis noticed that during bypass surgery, small amounts of tissue were being removed to run the bypass tubing into the heart, and surgeons were throwing it away after removal.
Davis, a BMES member, asked and was granted permission to use the tissue in his research lab for stem cell studies, according to the article. Davis began extracting and quantifying the stem cells, eventually finding that the young cells had more reparative qualities, and when injected into damaged tissue, released healing proteins.
Davis' first clinical trial with the stem cells (Autologous Cardiac Stem Cell Injection in Patients with Hypoplastic Left Heart Syndrome (ACT-HLHS) Trial) is happening in the next few months and has already been cleared by the FDA. Clinicians will inject the stem cells into the hearts of babies with CHD to boost the function of the heart.
“For a baby with HLHS, we are not going to re-grow the left ventricle, but rather try to strengthen and prevent deterioration of the existing right ventricle,” said Davis. “It sets the baby up for a successful repair surgery down the road.”
The 3D printing in Davis' lab is used to create valves, leaflets and patches.
Read more HERE.